Methylmalonyl-CoA mutase: Conversion of (R)-methylmalonyl-CoA to succinyl- CoA (degradation of odd- carbon fatty acids)
![Figure 1 from Methylmalonyl-coA epimerase deficiency: A new case, with an acute metabolic presentation and an intronic splicing mutation in the MCEE gene | Semantic Scholar Figure 1 from Methylmalonyl-coA epimerase deficiency: A new case, with an acute metabolic presentation and an intronic splicing mutation in the MCEE gene | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/121b92775cd34c5353d0cafcdaa16c9474c552a1/2-Figure1-1.png)
Figure 1 from Methylmalonyl-coA epimerase deficiency: A new case, with an acute metabolic presentation and an intronic splicing mutation in the MCEE gene | Semantic Scholar
![Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair | Science Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair | Science](https://www.science.org/cms/10.1126/science.aay0934/asset/1ea4ab06-a2e4-4fdb-973c-7a619ce6d71f/assets/graphic/366_589_f2.jpeg)
Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair | Science
![Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair | Science Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair | Science](https://www.science.org/cms/asset/7463fdbb-052a-4f0e-96dd-6a0930248c61/366_589_f1.gif)
Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair | Science
![Based on the mechanism for the methylmalonyl CoA mutase, a reasonable mechanism for the given reactions should be written. Concept Introduction: In the methylmalonyl CoA mutase reaction, a free radical is formed Based on the mechanism for the methylmalonyl CoA mutase, a reasonable mechanism for the given reactions should be written. Concept Introduction: In the methylmalonyl CoA mutase reaction, a free radical is formed](https://content.bartleby.com/tbms-images/9781305577206/Chapter-23/images/html_77206-23-16p_1.png)
Based on the mechanism for the methylmalonyl CoA mutase, a reasonable mechanism for the given reactions should be written. Concept Introduction: In the methylmalonyl CoA mutase reaction, a free radical is formed
![Figure 4 from Crystal structure of substrate complexes of methylmalonyl-CoA mutase. | Semantic Scholar Figure 4 from Crystal structure of substrate complexes of methylmalonyl-CoA mutase. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/5058d1e3896286e9b72bb6d8237c3ab98ece49ff/6-Figure4-1.png)
Figure 4 from Crystal structure of substrate complexes of methylmalonyl-CoA mutase. | Semantic Scholar
![Understanding the Mechanism of B12-Dependent Methylmalonyl-CoA Mutase: Partial Proton Transfer in Action | Journal of the American Chemical Society Understanding the Mechanism of B12-Dependent Methylmalonyl-CoA Mutase: Partial Proton Transfer in Action | Journal of the American Chemical Society](https://pubs.acs.org/cms/10.1021/ja991649a/asset/images/medium/ja991649ah00003.gif)
Understanding the Mechanism of B12-Dependent Methylmalonyl-CoA Mutase: Partial Proton Transfer in Action | Journal of the American Chemical Society
![Understanding the Mechanism of B12-Dependent Methylmalonyl-CoA Mutase: Partial Proton Transfer in Action | Journal of the American Chemical Society Understanding the Mechanism of B12-Dependent Methylmalonyl-CoA Mutase: Partial Proton Transfer in Action | Journal of the American Chemical Society](https://pubs.acs.org/cms/10.1021/ja991649a/asset/images/medium/ja991649ah00004.gif)
Understanding the Mechanism of B12-Dependent Methylmalonyl-CoA Mutase: Partial Proton Transfer in Action | Journal of the American Chemical Society
![Postulated reaction mechanism of methylmalonyl-CoA mutase. MCoA and... | Download Scientific Diagram Postulated reaction mechanism of methylmalonyl-CoA mutase. MCoA and... | Download Scientific Diagram](https://www.researchgate.net/profile/Agnieszka-Dybala-Defratyka/publication/6913551/figure/fig2/AS:667770505162762@1536220303459/Postulated-reaction-mechanism-of-methylmalonyl-CoA-mutase-MCoA-and-SCoA-refer-to_Q640.jpg)
Postulated reaction mechanism of methylmalonyl-CoA mutase. MCoA and... | Download Scientific Diagram
![What Triggers the Cleavage of the Co–C5′ Bond in Coenzyme B12-Dependent Itaconyl-CoA Methylmalonyl-CoA Mutase? | ACS Catalysis What Triggers the Cleavage of the Co–C5′ Bond in Coenzyme B12-Dependent Itaconyl-CoA Methylmalonyl-CoA Mutase? | ACS Catalysis](https://pubs.acs.org/cms/10.1021/acscatal.1c00291/asset/images/large/cs1c00291_0013.jpeg)
What Triggers the Cleavage of the Co–C5′ Bond in Coenzyme B12-Dependent Itaconyl-CoA Methylmalonyl-CoA Mutase? | ACS Catalysis
![Methylmalonyl-CoA Mutase Induction by Cerebral Ischemia and Neurotoxicity of the Mitochondrial Toxin Methylmalonic Acid | Journal of Neuroscience Methylmalonyl-CoA Mutase Induction by Cerebral Ischemia and Neurotoxicity of the Mitochondrial Toxin Methylmalonic Acid | Journal of Neuroscience](https://www.jneurosci.org/content/jneuro/16/22/7336/F7.large.jpg)
Methylmalonyl-CoA Mutase Induction by Cerebral Ischemia and Neurotoxicity of the Mitochondrial Toxin Methylmalonic Acid | Journal of Neuroscience
![The Coenzyme B12 Analog 5′-Deoxyadenosylcobinamide-GDP Supports Catalysis by Methylmalonyl-CoA Mutase in the Absence of Trans-ligand Coordination* - Journal of Biological Chemistry The Coenzyme B12 Analog 5′-Deoxyadenosylcobinamide-GDP Supports Catalysis by Methylmalonyl-CoA Mutase in the Absence of Trans-ligand Coordination* - Journal of Biological Chemistry](https://www.jbc.org/cms/asset/5c698c99-8764-4730-973f-30109e142207/gr1.jpg)
The Coenzyme B12 Analog 5′-Deoxyadenosylcobinamide-GDP Supports Catalysis by Methylmalonyl-CoA Mutase in the Absence of Trans-ligand Coordination* - Journal of Biological Chemistry
![Postulated reaction mechanism of methylmalonyl-CoA mutase. MCoA and... | Download Scientific Diagram Postulated reaction mechanism of methylmalonyl-CoA mutase. MCoA and... | Download Scientific Diagram](https://www.researchgate.net/publication/6913551/figure/fig2/AS:667770505162762@1536220303459/Postulated-reaction-mechanism-of-methylmalonyl-CoA-mutase-MCoA-and-SCoA-refer-to.png)
Postulated reaction mechanism of methylmalonyl-CoA mutase. MCoA and... | Download Scientific Diagram
![Characterization of a succinyl-CoA radical-cob(II)alamin spin triplet intermediate in the reaction catalyzed by adenosylcobalamin-dependent methylmalonyl-CoA mutase. - Abstract - Europe PMC Characterization of a succinyl-CoA radical-cob(II)alamin spin triplet intermediate in the reaction catalyzed by adenosylcobalamin-dependent methylmalonyl-CoA mutase. - Abstract - Europe PMC](https://europepmc.org/articles/PMC3132558/bin/nihms301910f1.jpg)
Characterization of a succinyl-CoA radical-cob(II)alamin spin triplet intermediate in the reaction catalyzed by adenosylcobalamin-dependent methylmalonyl-CoA mutase. - Abstract - Europe PMC
Methylmalonyl-CoA mutase: Conversion of (R)-methylmalonyl-CoA to succinyl- CoA (degradation of odd- carbon fatty acids)
![Figure 24-17Schematic representation of the thylakoid membrane showing the components of its electron-transport chain. Page ppt download Figure 24-17Schematic representation of the thylakoid membrane showing the components of its electron-transport chain. Page ppt download](https://images.slideplayer.com/17/5313463/slides/slide_32.jpg)
Figure 24-17Schematic representation of the thylakoid membrane showing the components of its electron-transport chain. Page ppt download
![Quantum catalysis in B12-dependent methylmalonyl-CoA mutase: experimental and computational insights | Philosophical Transactions of the Royal Society B: Biological Sciences Quantum catalysis in B12-dependent methylmalonyl-CoA mutase: experimental and computational insights | Philosophical Transactions of the Royal Society B: Biological Sciences](https://royalsocietypublishing.org/cms/asset/8352c07c-b423-4fb4-8872-e3812c5d2a3f/1333fig1.jpg)